Phylogenetics to help predict active metabolism

Genetypes: a concept to help integrate molecular phylogenetics and taxonomy

In order to better integrate molecular phylogenetics and taxonomy, genetic sequences from type materials should be explicitly identified in publications using a consistent nomenclature. Despite relatively frequent sampling of sequences from types (particularly topotypes—samples from the type locality), the practice of explicitly noting that these materials were sampled is uncommon. Because of t...

Using genomics to help predict drug interactions

This article proposes using genomic information to help tailor the output of a drug interaction program for a patient. This paper focuses on a particular CYP450 enzyme to illustrate adding genomic information to an existing drug interaction database. The data are formatted as an Extensible Markup Language (XML) document. The additional interaction information based on genomics for a patient is ...

Active Help Systems

Using neuroimaging to help predict the onset of psychosis

The aim of this review is to assess the potential for neuroimaging measures to facilitate prediction of the onset of psychosis. Research in this field has mainly involved people at 'ultra-high risk' (UHR) of psychosis, who have a very high risk of developing a psychotic disorder within a few years of presentation to mental health services. The review details the key findings and developments in...

may new biomarkers help us to predict progressive multifocal leukoencephalopathy in hiv positive people?

-